Jakafi's dominance in ultra-rare-disease indications establishes a moat.
In the second quarter, strong Jakafi product sales were partially offset by higher research and development expenses, as more of Incyte’s late-stage pipeline entered pivotal testing. Our full-year estimates for the rare disease drug fall in the top range of management’s updated range of $1.09 billion-$1.12 billion (from $1.02 billion-$1.07 billion), and we raised research and development costs in our model slightly over the next few years to account for Incyte’s robust pipeline progression. We a...Incyte is a biopharmaceutical company focused on the discovery, development and commercialization of therapeutics. JAKAFI (ruxolitinib) has been approved for the treatment of patients with intermediate or high-risk myelofibrosis, for the treatment of patients with polycythemia vera, and for the treatment of steroid-refractory acute graft-versus-host disease in adult and pediatric patients 12 years and older. The company has also obtained a license to develop and commercialize ICLUSIG (ponatinib) in Europe and other select countries. In the European Union, ICLUSIG is approved for the treatment of adult patients with chronic phase, accelerated phase or blast phase chronic myeloid leukemia.
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