Report
Karen Andersen
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Morningstar | Lowering Narrow-Moat United Therapeutics' FVE on Increased Costs, Continued Generic Headwinds. See Updated Analyst Note from 01 May 2019

United Therapeutics reported first-quarter revenue of about $363 million, down about 7% from last year. The results were helped by volume and price increases, including Remodulin's first price increase in nearly a decade. Remodulin contributed $156 million, up 23% from last year. After some adjustments to our model, including United's first-quarter up-front payment of $800 million to Arena Pharmaceuticals for ralinepag and a lowered outlook for Adcirca and Tyvaso, we are lowering our fair value estimate to $117 per share from $127. Despite this year's price increases, we model total revenue declines through 2021 due to patent expirations and generic entry. However, United has made solid progress in fortifying its pipeline, and we think new product revenue will keep returns above its cost of capital, solidifying its narrow economic moat.

Tyvaso continues to contribute significantly to United's top line, with $104 million in revenue representing a 10% increase from last year, driven by both price and volume, and a single-digit decrease sequentially. Orenitram also benefited from price and volume, posting $58 million, up 12% from last year. Unituxin contributed $25 million in revenue, up 38% from last year, primarily driven by volume. Adcirca sales declined more rapidly than we had projected, with $20 million representing an 80% decrease from last year and over 50% decrease sequentially. We've lowered our outlook for Adcirca and expect continued declines following last year's generic entry.
Underlying
United Therapeutics Corporation

United Therapeutics is a biotechnology company. The company markets and sells four commercial therapies to treat pulmonary arterial hypertension (PAH): Remodulin? (treprostinil) Injection; Tyvaso? (treprostinil) Inhalation Solution; Orenitram? (treprostinil) Extended-Release Tablets; and Adcirca? (tadalafil) Tablets. The company also markets and sells an oncology product, Unituxin? (dinutuximab) Injection for treatment of high-risk neuroblastoma. The company also engages in research and development of new indications and formulations and delivery devices for its existing products, as well as new products to treat PAH and other conditions. The company also engages in organ transplantation-related technologies.

Provider
Morningstar
Morningstar

Morningstar, Inc. is a leading provider of independent investment research in North America, Europe, Australia, and Asia. The company offer an extensive line of products and services for individual investors, financial advisors, asset managers, and retirement plan providers and sponsors.

Morningstar provides data on approximately 530,000 investment offerings, including stocks, mutual funds, and similar vehicles, along with real-time global market data on more than 18 million equities, indexes, futures, options, commodities, and precious metals, in addition to foreign exchange and Treasury markets. Morningstar also offers investment management services through its investment advisory subsidiaries and had approximately $185 billion in assets under advisement and management as of June 30, 2016.

We have operations in 27 countries.

Analysts
Karen Andersen

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