Report
Dominic Rose ...
  • Naresh Chouhan
EUR 4383.50 For Business Accounts Only

AZN – Pipeline Continues to Drive Upgrades (BUY, TP £100 [95], 14 pgs)

AZN continue to outperform our expectations from the pipeline. The recent Lynparza prostate cancer & Enhertu HER2-low data have driven an 8% upgrade to 2027 EBIT and led us to increase our PT to £100. Our in-depth analysis of the two indications has led to a $2bn upgrade to our Lynparza sales & a $1.9bn upgrade to Enhertu global sales, meaning we now forecast peak sales of $7bn and $10bn, respectively. AZN will be hosting an investor event tonight which will further elucidate the Lynparza prostate opportunity & could drive consensus upgrades. There is material further upside to come given 6 Enhertu trials in ‘23, from which we assume very little.
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Underlying
AstraZeneca PLC

AstraZeneca is a holding company. Through its subsidiaries, Co. operates as a biopharmaceutical company engaged in discovering, developing, manufacturing and commercializing its pipeline of small molecule and biologic prescription medicines, including targeted business development through collaboration, in-licensing and acquisitions. Co. is focused on three main therapy areas: Oncology, Cardiovascular and Metabolic Diseases, and Respiratory. Co. is also selectively active in autoimmunity, infection and neuroscience. In addition, Co. works across small molecules, oligonucleotides and other drug platforms, as well as biologic medicines.

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New Street Research
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Analysts
Dominic Rose

Naresh Chouhan

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