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Guy Sips ... (+6)
  • Guy Sips
  • Hilde Van Boxstael
  • Jacob Mekhael
  • Kristof Samoy
  • Sharad Kumar S.P
  • Wim Lewi
 PRESS RELEASE

Inventiva annonce la recommandation positive du quatrième DMC de l’étu...

Inventiva annonce la recommandation positive du quatrième DMC de l’étude clinique NATiV3 Phase III avec lanifibranor dans la MASH/NASH Le Data Monitoring Committee recommande sur la base d’une revue planifiée des données de sécurité que l’étude clinique de Phase III continue sans modification du protocole actuel.L’évaluation réalisée par le DMC est basée sur l’examen non masqué des données de sécurité provenant de plus de 900 patients randomisés dans les cohortes principale et exploratoire, incluant respectivement plus de 360 et plus de 80 patients ayant été traités pendant plus de 48 et 72...

 PRESS RELEASE

Inventiva announces the positive recommendation of the fourth DMC of t...

Inventiva announces the positive recommendation of the fourth DMC of the NATiV3 Phase III clinical trial with lanifibranor in patients with MASH/NASH The Data Monitoring Committee recommended to continue the clinical trial without modification of the current protocol, based on the pre-planned review of safety data.The recommendation was based on the unblinded review by the DMC of safety data from more than 900 patients randomized in the main and exploratory cohorts, including more than 360 and 80 patients that have been treated for more than 48 and 72 weeks, respectively.The patient who exp...

UCB SA: 2 directors

Two Directors at UCB SA sold/bought 4,187 shares at 129.920USD. The significance rating of the trade was 87/100. Is that information sufficient for you to make an investment decision? This report gives details of those trades and adds context and analysis to them such that you can judge whether these trading decisions are ones worth following. Included in the report is a detailed share price chart which plots discretionary trades by all the company's directors over the last two years clearly s...

Guy Sips ... (+4)
  • Guy Sips
  • Jacob Mekhael
  • Sharad Kumar S.P
  • Wim Hoste
Jacob Mekhael
  • Jacob Mekhael

Inventiva Additional NATIVE data supportive of lanifibranor's benefit ...

Yesterday, Inventiva announced the publication of additional results from the phase 2 (NATIVE) trial of lanifibranor in MASH (previously NASH), which are in line with previously reported benefits on cardiometabolic outcomes, leading the stock to trade +7% intraday. We believe the results continue to support lanifibranor's positioning in MASH, and look forward to the last patient first visit (expected by 1H24) in the phase 3 (NATiV3) trial. We reiterate our BUY rating and € 10 TP.

 PRESS RELEASE

Fagron shareholders approve all voting items at AGM and EGM

Fagron shareholders approve all voting items at AGM and EGM Regulated informationNazareth (Belgium)/Rotterdam (The Netherlands), 13 May 2024 – 7PM CET Fagron shareholders approve all voting items at AGM and EGM Fagron, the leading global player in pharmaceutical compounding, held its annual general meeting of shareholders and extraordinary general meeting of shareholders today. Both meetings approved all. voting items. ResolutionsThe annual general meeting approved, amongst other things, Fagron’s annual financial statements and dividend proposal of €0.30 per share for the fiscal year 20...

 PRESS RELEASE

Aandeelhouders Fagron keuren alle stempunten AVA en BAVA goed

Aandeelhouders Fagron keuren alle stempunten AVA en BAVA goed Gereglementeerde informatieNazareth (België)/Rotterdam (Nederland), 13 mei 2024 – 19:00u CET Aandeelhouders Fagron keuren alle stempunten AVA en BAVA goed Fagron, de toonaangevende mondiale speler in farmaceutische bereidingen, hield vandaag haar jaarlijkse algemene vergadering van aandeelhouders en buitengewone algemene vergadering van aandeelhouders. Beide vergaderingen keurden alle voorgelegde besluiten goed. BesluitenDe algemene jaarvergadering heeft onder andere Fagron’s jaarrekening en het dividendvoorstel van €0,30 per ...

 PRESS RELEASE

Inventiva announces the publication in Nature Communications of additi...

Inventiva announces the publication in Nature Communications of additional results from NATIVE Phase IIb clinical trial demonstrating improvement of markers of cardiometabolic health in patients with MASH/NASH treated with lanifibranor Improvements were observed for insulin resistance (insulin levels, HOMA-IR), lipid metabolism (triglycerides, HDL-cholesterol, apolipoproteins), control of glycemia (HbA1c, fasting glucose (FG) levels), systemic inflammation (hs-CRP, ferritin), hepatic steatosis and diastolic blood pressure.Among the patients who had prediabetes at study entry and were treate...

 PRESS RELEASE

Inventiva annonce la publication dans Nature Communications de résulta...

Inventiva annonce la publication dans Nature Communications de résultats complémentaires de l’étude clinique de Phase II NATIVE démontrant l’amélioration de marqueurs de santé cardiométabolique chez les patients atteints de MASH/NASH traité Des améliorations ont été observées au niveau de la résistance à l'insuline (taux d'insuline, HOMA-IR), du métabolisme lipidique (triglycérides, HDL-cholestérol, apolipoprotéines), du contrôle de la glycémie (HbA1c, taux de glucose à jeun), de l'inflammation systémique (hs-CRP, ferritine), de la stéatose hépatique et de la pression artérielle diastolique...

ING Helpdesk
  • ING Helpdesk

Benelux Morning Notes

Aperam: In-line 1Q24 EBITDA, FCF marked by WC build, 2Q24 guidance below consensus. Ayvens: Taking the brakes off. BAM: Not the best start to the year. bpost: 1Q24 in line with consensus but beat vs INGF, no outlook yet. Brunel International: good set of 1Q24 results – 5% beat on EBIT, comforting trends. B&S Group: Preview - should be a non-event. DEME Group: Preview - should be a non-event. D'Ieteren: Febiac April registrations flat YoY, VW brands up 8.4%. GBL: NAV per share in ...

ING Helpdesk
  • ING Helpdesk

Benelux Morning Notes

Aedifica: First sign of portfolio valuation stabilization. ArcelorMittal: Solid 1Q24 EBITDA beat, softer FCF reflects WC and CAPEX phasing. Belgian telcos: Peer Telenet 1Q24 results, still weak commercial performance. dsm-firmenich AG: Vita-still not-min. IBA: Contract to install a P1 system in Connecticut. KPN: VodafoneZiggo 1Q24 results confirm fixed losses, mobile weaker QoQ. Shell plc: Good start to the year

Guy Sips ... (+8)
  • Guy Sips
  • Hilde Van Boxstael
  • Jacob Mekhael
  • Lynn Hautekeete
  • Michiel Declercq
  • Thomas Couvreur
  • Wim Hoste
  • Wim Lewi
Stefano Toffano
  • Stefano Toffano

DSM-Firmenich : Slowly returning to growth

>No major surprises - DSM-Firmenich posted a relatively weak but in line quarter, with no major surprises on the group level compared to previous communication. The challenging destocking and pricing environment in mainly ANH’s and HNC’s end-markets fed into 2024, resulting in Q1 24 pro-forma revenues and adj. EBITDA of c. € 3,071m (-2% yoy) and € 463m (-11% yoy) respectively, the latter roughly reflecting ccs and AAOB estimates. In line with previous communication, D...

Wim Hoste
  • Wim Hoste

DSM-Firmenich FIRST LOOK :1Q adj EBITDA -11%, FY guidance maintained

1Q adj EBITDA decreased by 11% which was close to our and consensus forecasts. Dsm-firmenich expects to see higher vitamin prices as from 2Q and reiterated FY guidance of at least € 1.9bn adjusted EBITDA, with our and consensus forecasts close to € 2bn. The carve out of Animal Nutrition & Health has started and based on a gradual improvement of market conditions as well as earnings support from the € 200m vitamin restructuring program, we believe proceeds of € 3.0-3.5bn for ANH to be possible, w...

Fernand de Boer
  • Fernand de Boer

DSM Firmenich - Results in line with CSS, but better quality

Q1-24 sales and EBITDA were in line with CSS and exceeding our estimate. However, the return of volume growth and nice beat in high valued segments Perfumery & Beauty and Taste Texture & Beyond should be positively received. We reiterate our Buy rating and lift our TP from EUR 120 to EUR 129.

Kristof Samoy ... (+5)
  • Kristof Samoy
  • Michiel Declercq
  • Sharad Kumar S.P
  • Thomas Vranken
  • Wim Hoste
Thomas Vranken
  • Thomas Vranken

UCB Model update: UCB's five growth drivers into the next decade

UCB is entering a next stage of growth as it turns the page on the loss of exclusivity of several of its mature assets. The new chapter will focus strongly on five growth drivers: Bimzelx, Rystiggo, Zilbrysq, Fintepla and Evenity. Jointly, these assets could deliver significant topline growth and margin improvements in the coming years. We have conducted an extensive update of our model to incorporate these new dynamics. Our DCF-based valuation points to a fair value of € 143 per share (previous...

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