2U is provider of education technology for nonprofit colleges and universities. The company builds, delivers, and supports digital and in-person educational offerings, including graduate degrees, undergraduate degrees, professional certificates, boot camps, and short courses, across the career curriculum continuum. In its Graduate Program Segment, the company provides the technology and services to nonprofit colleges and universities to enable the online delivery of degree programs. In its Alternative Credential Segment, the company provides online short courses and technical, skills-based boot camps through relationships with nonprofit colleges and universities.

ABIOMED is a provider of temporary mechanical circulatory support devices, and it provides a continuum of care to heart failure patients. The company's products include: Impella 2.5?, which is a percutaneous micro heart pump with an integrated motor and sensors; which is primarily used by either interventional cardiologists to support patients in the cath lab or by cardiac surgeons in the heart surgery suite; Impella 5.0 and Impella LD, which are percutaneous micro heart pumps with integrated motors and sensors for use primarily in the heart surgery suite; and Impella RP, which is a percutaneous catheter-based axial flow pump that is designed to allow more than four liters of flow per minute.

Acceleron Pharma is a biopharmaceutical company focused on the discovery, development and commercialization of therapeutics to treat diseases. The company has focused its research and development activities in three primary therapeutic areas: hematology, pulmonary and neuromuscular. The company's commercial product, REBLOZYL? (luspatercept-aamt) for the treatment of anemia in adult patients with beta-thalassemia who require regular red blood cell transfusions. The company is also developing its key pulmonary program, sotatercept, for the treatment of patients with pulmonary arterial hypertension. The company is developing its neuromuscular candidate, ACE-083, which is designed for the treatment of focal muscle disorders.

ACM Research supplies capital equipment developed for the semiconductor industry. The company's tools for use in fabricating foundry, logic and memory chips, including dynamic random-access memory and 3D NAND-flash memory chips. The company also develops, manufactures and sells a range of packaging tools to wafer assembly and packaging customers. The company's technology and product include: Single Wafer Wet Cleaning Equipment for Front End Production Processes, which consist of its proprietary Space Alternated Phase Shift, Timely Energized Bubble Oscillation and Single-Wafer Tools for Back-End Assembly and Packaging, which provides a range of single-wafer tools for back-end wafer assembly and packaging factories.

Activision Blizzard is a global developer and publisher of interactive entertainment content and services. The company's segments are: Activision Publishing, Inc., which is a global developer and publisher of interactive software products and entertainment content, particularly for the console platform; Blizzard Entertainment, Inc., which is a global developer and publisher of interactive software products and entertainment content, particularly for the personal computers platform; and King Digital Entertainment, which is a global developer and publisher of interactive entertainment content and services, particularly for the mobile platform, including for Google Inc.'s Android and Apple Inc.'s iOS.

Agnico-Eagle Mines is a gold mining company with mining operations in Canada, Mexico and Finland. Co. earns a proportion of its revenues from the production and sale of gold in both dore bar and concentrate form. The remainder of revenue and cash flow is generated by the production and sale of byproduct metals. The revenue from byproduct metals is mainly generated by production at the LaRonde mine in Canada (silver, zinc, copper and lead) and the Pinos Altos mine in Mexico (silver).

Akebia Therapeutics is a biopharmaceutical company focused on the development and commercialization of therapeutics for people living with kidney disease. The company's portfolio includes: Vadadustat, which is an investigational, oral hypoxia-inducible factor prolyl hydroxylase inhibitor for two indications, anemia due to chronic kidney disease (CKD), in adult patients on dialysis, and anemia due to CKD in adult patients not on dialysis; and Auryxia? (ferric citrate), for the control of serum phosphorus levels in adult patients on dialysis, or the Hyperphosphatemia Indication, and the treatment of iron deficiency anemia (IDA) in adult patients not on dialysis, or the IDA Indication;

Alarm.com is a platform for the intelligently connected property. The company provides a suite of cloud-based solutions for smart residential and commercial properties. The company's service provider partners can deploy its interactive security, video monitoring, intelligent automation and energy management solutions as stand-alone offerings or as combined solutions to address the needs of a range of customers. The company's subscribers can connect to their property through the company's family of mobile apps, websites, and engagement platforms like voice control through Amazon Echo and Google Home, wearable devices like the Apple Watch and TV platforms such as Apple TV and Amazon Fire TV.

Allogene Therapeutics is a clinical stage immuno-oncology company focused on the development and commercialization of genetically engineered allogeneic T cell therapies for the treatment of cancer. Several of the company's key product candidates, including UCART19, ALLO-501 and ALLO-501A, are engineered allogeneic CAR T cell therapies that target CD19, a protein expressed on the cell surface of B cells and a validated target for B cell driven hematological malignancies. The company is developing an anti-CD52 monoclonal antibody, ALLO-647, which is designed to be used prior to infusing its other product candidates as part of the lymphodepletion regimen.

Allot Communications is a provider of network intelligence and security solutions for mobile and fixed service providers as well as enterprises worldwide. Co.'s solutions are deployed for network and application analytics, traffic control and shaping, network-based security including mobile security, Denial of Service protection, IoT security, and more. Co.'s Network Intelligence solutions include: Analytics, which delivers network business intelligence; Traffic Management, which prioritizes critical network traffic, control congestion and optimize service delivery; Policy Control and Charging, which drives personalized service plans and pay-for-use pricing models; and Service Enablement.

Amphastar Pharmaceuticals is a pharmaceutical company focused on developing, manufacturing, marketing and selling generic and injectable, inhalation, and intranasal products, as well as insulin active pharmaceutical ingredient. The company has two reportable segments: finished pharmaceutical products and active pharmaceutical ingredients (API) products. The finished pharmaceutical products segment manufactures, markets and distributes enoxaparin, naloxone, phytonadione, lidocaine, medroxyprogesterone acetate, Primatene? Mist, as well as various other critical and non-critical care drugs. The API segment manufactures and distributes recombinant human insulin API and porcine insulin API.

Apple designs, manufactures and markets smartphones, personal computers, tablets, wearables and accessories, and sells a variety of related services. The company's products include: iPhone; Mac; iPad; and wearables, home and accessories, which includes AirPods?, Apple TV?, Apple Watch?, Beats? products, HomePod?, iPod touch? and other Apple-branded and third-party accessories. The company's services include: digital content stores and streaming services; AppleCare, which includes AppleCare + (AC+) and the AppleCare Protection Plan; iCloud, which is the company's cloud service; licensing; and other services, which include Apple Arcade?, Apple Card?, Apple News+, and Apple Pay, a cashless payment service.

AtriCure is a provider of treatments for atrial fibrillation and left atrial appendage management. The company provides product lines for left atrial appendage management and open and minimally invasive cardiac tissue ablation. The company's Radio Frequency Ablation devices include; CryoICE Cryoablation System, which is used in open ablation procedures and consists of the cryoICE Box generator along with a single-use disposable probe; EPi-Sense Guided Coagulation System with VisiTrax Technology, which utilizes monopolar energy for the coagulation of tissue; and LARIAT System, which is a suture-based solution for soft-tissue closure and is compatible with a range of anatomical shapes.

AudioCodes designs, develops and sells products and services for voice and data over packet networks. Voice over packet, or VoP, networks consist of key network elements such as software switches, application servers, Internet protocol (IP) phones, media gateways and session border controllers (SBC). Co.'s products primarily provide the media gateway and SBC element in the network, as well as voice over Internet protocol, or VoIP, end-points such as IP Phones and VoIP mobile clients. Multi-service business routers integrate media gateway functionality with data routing and network access. The media gateways connect legacy and IP networks.

Avantor is a global provider of mission critical products and services to customers in the biopharma, healthcare, education and government, and advanced technologies and applied materials industries. The company's comprehensive offerings, which include materials & consumables, equipment & instrumentation and services and specialty procurement, are relied upon by its customers, often on a recurring basis, because they are frequently specified into their research, development and production processes. The company operates in more than 30 countries and deliver an extensive portfolio of mission critical products, services and solutions.

Axcelis Technologies designs, manufactures and services ion implantation and other processing equipment used in the fabrication of semiconductor chips. The company also provides aftermarket lifecycle products and services, including used tools, spare parts, equipment upgrades, maintenance services and customer training. The company provides high energy, high current and medium current implanters for all application requirements. The company's Purion systems are all based on a common platform which enables a combination of implant purity, precision and productivity by combining a single wafer end station, with a spot beam architecture. The company's other products include curing systems, and thermal processing systems.

Axcella Health is a biotechnology company pioneering the research and development of novel multifactorial interventions to support health and address dysregulated metabolism across a broad spectrum of consumers and patients who have limited options. The company's AXA Candidates are generated from its proprietary, human-focused AXA Development Platform and harness the power of endogenous metabolic modulators, or EMMs, a broad family of molecules that fundamentally impact and regulate human metabolism.

Bio-Rad Laboratories is a manufacturer and distributor of its own life science research and clinical diagnostics products. The company has two primary segments: Life Science, which is engaged in the life sciences market and develops, manufactures and markets reagents, apparatus and laboratory instruments; and Clinical Diagnostics, which designs, manufactures, sells and supports test systems, informatics systems, test kits and quality controls that serve clinical laboratories in the diagnostics market. The company sells its products and services to a client base comprised of scientific research, healthcare, education and government customers.

Bio-Techne and its subsidiaries develop, manufacture and sell biotechnology life science reagents, instruments and services for the research and clinical diagnostic markets.Co.'s segments: Protein Sciences, which developes and manufactures purified proteins and reagent solutions, cytokines and growth factors, antibodies, immunoassays, biologically active small molecule compounds, tissue culture reagents and T-Cell activation technologies; and Diagnostics and Genomics, which develops and manufactures diagnostic products, including Food and Drug Administration-regulated controls, calibrators, blood gas and clinical chemistry controls and other reagents for Original Equipment Manufacturer.

BioXcel Therapeutics is a clinical stage biopharmaceutical company utilizing artificial intelligence to identify therapies in neuroscience and immuno-oncology. The company's drug approach utilize existing approved drugs and/or clinically validated product candidates together data and proprietary machine learning algorithms to identify new therapeutic indices. The company's clinical development programs are BXCL501, which is designed for acute treatment of agitation resulting from neuropsychiatric disorders, and BXCL701, which is designed for treatment of a rare form of prostate cancer, pancreatic cancer and cancers in combination with other immuno-oncology agents.

Catalent is a holding company. Through its subsidiaries, the company is a provider of delivery technologies and development solutions for drugs, biologics and consumer health products. The company operates in four segments: Softgel Technologies, which provides formulation, development and manufacturing services for soft capsules; Biologics and Specialty Drug Delivery, which provides drug substance development and manufacturing; Oral Drug Delivery, which provides various formulation development and manufacturing technologies; and Clinical Supply Services, which provides manufacturing, packaging, storage, distribution, project management, and inventory management for drugs and biologics in clinical trials.

Central Garden & Pet is a producer and distributor of products for the lawn and garden and pet supplies markets. The company has two segments, Pet and Garden. In Pet segment, the company is a marketer and producer of pet supplies. The company's principal pet supplies categories are dog and cat, aquatics, bird and small animal, wild bird feed, live fish and small animal, and animal health products. In Garden segment, the company markets and produces a range of brands, including Pennington, The Rebels, AMDRO, Lilly Miller, Ironite, Sevin, and Over-N-Out. The company's principal lawn and garden product lines are grass seed, wild bird feed, insect control products, lawn and garden care products, and decorative outdoor patio products.

ChannelAdvisor is a provider of software-as-a-service (SaaS) solutions. The primary products the company provides are: Marketplaces module, which connects customers to third-party marketplaces such as Amazon, eBay, Google, Newegg, Overstock.com, Rakuten, Target, TradeMe, Walmart and Zalando; and Digital Marketing module, which connects customers to comparison shopping websites such as Google Shopping and Shopzilla, allows customers to advertise products on search engines such as Google and Microsoft's Bing, connects customers to social commerce sites such as Facebook, Instagram and Pinterest and supports advertising programs on some marketplaces such as Amazon and eBay.

Charles River Laboratories International is a contract research organization. The company has a laboratory animal medicine and science to develop a portfolio of discovery and safety assessment services. The company's segments are: Research Models and Services, which supplies research models to the drug development industry; Discovery and Safety Assessment (DSA), which provides DSA services, including in vitro and in vivo studies, laboratory support services, and strategic non-clinical consulting and program management to support product development; and Manufacturing Support, which ensures the production and release of products manufactured by the company's clients.

Cognex is a provider of machine vision products that capture and analyze visual information in order to automate manufacturing and distribution tasks where vision is required. Machine vision products are used to automate the manufacture and tracking of discrete items, such as mobile phones, aspirin bottles, and automobile tires, by locating, identifying, inspecting, and measuring them during the manufacturing or distribution process. The company provides a range of machine vision systems and sensors, vision software, and industrial image-based barcode readers. The company's products also have a variety of physical forms, depending upon the user's needs.

Constellation Pharmaceuticals is a clinical-stage biopharmaceutical company using its capabilities in epigenetics to discover and develop therapeutics that address medical needs in patients with cancers associated with abnormal gene expression or drug resistance. The company's integrated epigenetics platform enables it to validate targets and generate small molecules against these targets that selectively modulate gene expression in tumor and immune cells to drive anti-tumor activity. The company has three product candidates: CPI-0610, CPI-1205, and CPI-0209. CPI-0610 inhibits bromodomain and extra terminal domain proteins. CPI-1205 and CPI-0209 inhibit the enhancer of zeste homolog 2 protein.

Coupa Software is a provider of business spend management (BSM) solutions. The company provides a cloud-based BSM platform that delivers a range of capabilities that would typically require the purchase and use of multiple disparate point applications. The company's main platform consists of procurement, invoicing, expense management and payments modules that form the transactional engine for managing a company's business spend. In addition, the company's platform provides supporting modules to help companies further manage their spend, including strategic sourcing, spend analysis, contract management, supplier management, and contingent workforce management.

CytomX Therapeutics is clinical-stage, oncology-focused biopharmaceutical company with a class of investigational antibody therapeutics based on its Probody? technology platform the treatment of cancer. The company uses its platform to create proprietary cancer immunotherapies against clinically-validated targets. The company's two programs, CX-072, a wholly owned PD-L1-targeting Probody therapeutic and CX-2009, wholly owned CD166-targeting Probody drug conjugate. Both CX-072 and CX-2009 are part of PROCLAIM (Probody Clinical Assessment in Man), an international umbrella clinical trial program that provides clinical trial sites with access to the company's novel therapies under one central protocol.

Cytosorbents is engaged in critical care immunotherapy, investigating and commercializing its CytoSorb blood purification technology to reduce uncontrolled inflammation in hospitalized patients around the world, to prevent or treat multiple organ failure in life-threatening illnesses and cardiac surgery. CytoSorb, the company's primary product, is approved in the European Union as an extracorporeal cytokine filter and is designed to reduce the cytokine storm that could otherwise cause massive inflammation, organ failure and death in common critical illnesses such as sepsis, burn injury, trauma, lung injury, and pancreatitis. CytoSorb is used during and after cardiac surgery.

Dropbox is a global collaboration platform that centralizes the flow of information between the products and services its users prefer. Dropbox allows individuals, teams, and organizations to collaborate. Anyone can sign up for free via the company's website or app, and upgrade to a paid subscription plan for additional features. Dropbox is a digital workspace where individuals and teams can create content, access it from anywhere, and share it with collaborators. The company also utilizes Amazon Web Services (AWS), for the remainder of its users' storage needs and to help deliver its services. These AWS datacenters are in the United States and Europe, which allows the company to localize where content is stored.

Dynatrace is a software intelligence company. The company is engaged in providing services such as application performance management, artificial intelligence for operations, cloud infrastructure monitoring, and digital experience management, with products for the information technology departments and digital business owners of medium and large businesses. The company's primary offering is the Dynatrace Software Intelligence Platform, or Dynatrace?. The company's platform provides software-as-a-service, or SaaS, with the customer option of either maintaining data in the cloud, or at the edge in customer-provisioned infrastructure, which the company refers to as Dynatrace? Managed.

Emergent BioSolutions is a life sciences company. The company is focused on preparedness and response products and solutions that address the following categories: Chemical, Biological, Radiological, Nuclear and Explosives; emerging infectious diseases; travel health; emerging health crises; acute/emergency care; and contract development and manufacturing. The company also has a development pipeline consisting of a mix of both pre-clinical and clinical-stage product candidates, including Trobigard? a combination drug-device auto injector product candidate. In addition, the company has a fully integrated molecule-to-market biologics CDMO business offerings (development services, drug substance and drug product).

Enbridge is an energy transportation and distribution companyoperating in 5 segments: Liquids Pipelines, consists of common carrier and contract crude oil, natural gas liquids and refined products pipelines and terminals; Gas Distribution, of Co.'s natural gas utility operations; Gas Pipelines and Processi consists of investments in natural gas pipelines and processing facilities; Green Power and Transmission, consists of Co.'s investments in renewable energy assets and transmission facilities; and Energy Services, consist of physical commodity marketing activity and logistical services.

Enphase Energy is a global energy technology company. The company designs, develops, manufactures and sells home energy solutions that connect energy generation, energy storage and control and communications management on one platform. The company's semiconductor-based microinverter converts energy at the individual solar module level and, combines with its proprietary networking and software technologies to provide energy monitoring and control. The Enphase Home Energy Solution with IQ consists of four primary components: Enphase microinverters, the AC Battery?, an Envoy gateway, and Enlighten cloud-based software.

Entegris is a developer, manufacturer and supplier of microcontamination control products, chemicals and materials handling solutions for manufacturing processes in the semiconductor and other industries. The company has three segments: Specialty Chemicals and Engineered Materials, which provides process chemistries, gases, and materials; Microcontamination Control, which provides solutions to filter and purify liquid chemistries and gases used in semiconductor manufacturing processes and other industries; and Advanced Materials Handling segment, which develops solutions to monitor, protect, transport, and deliver liquid chemistries, wafers and substrates.

Everbridge is a software company that provides enterprise software applications that automate and accelerate organizations' operational response to events in order to keep people safe and businesses running. Through its Critical Event Management platform, the company delivers applications that provide organizations with the ability to assess threats, locate people, automate actions, monitor incident response, and deliver contextual communications in any volume, in near-real time. The company's applications include mass notification, safety connection, incident management, information technology alerting, visual command center, public warning, community engagement , crisis management, and secure messaging.

F5 Networks is a provider of multi-cloud application services, which enable its customers to develop, deploy, operate, secure, and govern applications in any architecture, from on-premises to the public cloud. The company's application services are available as cloud-based, software-as-a-service, and software-only solutions supported for multi-cloud environments. In connection with its solutions, the company provides a range of services, including consulting, training, installation, maintenance, and other technical support services. The company's products and solutions include hardware platforms, software and software-as-a-service platforms, cloud-based managed services, and service provider solutions.

Fastenal is engaged in the wholesale distribution of industrial and construction supplies. The company is a distributor of fasteners and related industrial and construction supplies. This includes threaded fasteners, bolts, nuts, screws, studs, and related washers, as well as miscellaneous supplies and hardware, such as pins, machinery keys, concrete anchors, metal framing systems, wire rope, strut, rivets, and related accessories. The company's fastener product line is primarily sold under the Fastenal product name.

Fortinet provides cybersecurity solutions. The company's product offerings consist of its FortiGate product family and its non-FortiGate products. The company's FortiGate hardware and software licenses are sold with a set of security services. These security services are enabled by FortiGuard, which provides threat research and artificial intelligence capabilities from a global cloud network to deliver protection services to each FortiGate appliance. The company's non-FortiGate products include the Fortinet Security Fabric (such as FortiAP, FortiAnalyzer, FortiSwitch and FortiManager), certain cloud security products (such as virtual machines and cloud services) and other products.

Grand Canyon Education is an educational services company focused on providing support services to institutions in the post-secondary education sector. The company's services include: Technical and Academic Services, which provides services that relate to the ongoing maintenance of its client's educational infrastructure, including online course delivery and management, student records, assessment, customer relations management and other internal administrative systems; Counseling Services and Support, which includes team-based counseling and other support for prospective and existing students of its client as well as financial aid processing; Marketing and Communication; and Back Office Services.

Halozyme Therapeutics is a biopharma technology platform company that provides solutions to improve patient experience and outcomes. The company's approved product and its collaborators' approved products and product candidates are based on rHuPH20, its patented recombinant human hyaluronidase enzyme. The company refers to the application of rHuPH20 to facilitate the delivery of other drugs or fluids as its ENHANZE? Drug Delivery Technology (ENHANZE). The company licenses the ENHANZE technology to form collaborations with biopharmaceutical companies that develop or market drugs requiring or benefiting from injection via the subcutaneous route of administration.

IDEXX Laboratories develops, manufactures, and distributes products and provides services primarily for the companion animal veterinary, livestock and poultry, dairy and water testing markets. The company operates primarily through three business segments: Companion Animal Group, which provides diagnostic and information management-based products and services for the veterinary market; Water Quality Products, which designs, develops, manufactures, and distributes products used in the detection of various microbiological parameters in water; and Livestock, Poultry and Dairy, which provides diagnostic products and services for livestock and poultry health.

II-VI develops, manufactures, and markets engineered materials, optoelectronic components, and devices for a range of applications. The company has three segments: II-VI Laser Solutions, which designs, manufactures, and markets optical and electro-optical components and materials sold under the II-VI Infrared brand name; II-VI Photonics, which manufactures crystal materials, optics, microchip lasers, and optoelectronic modules for use in optical communication networks and other consumer applications; and II-VI Performance Products, which designs, manufactures, and markets infrared optical components and optical assemblies for aerospace and defense, medical and commercial laser imaging applications.

Inphi is a provider of analog and mixed signal semiconductor solutions for the communications and datacenter markets. The company's analog and mixed signal semiconductor solutions provide an interface between analog and mixed signals and digital information in systems such as telecommunications transport systems, enterprise networking equipment and datacenters. The company has a range of products in its portfolio, including products that have commercially shipped, products for which the company has shipped engineering samples and products under development, that perform a range of functions such as amplifying, encoding, multiplexing, demultiplexing, and retiming signals at speeds up to 400 Gbps.

Insulet is engaged in the development, manufacturing and sale of its Omnipod? System, an insulin delivery system for people with insulin-dependent diabetes, which consists of two product lines: the Omnipod Insulin Management System and Omnipod DASH? Insulin Management System. The Omnipod System features a self-adhesive disposable tubeless Pod, which is worn on the body and provides up to three days of non-stop insulin delivery without the need to see or handle a needle, and a handheld Personal Diabetes Manager. The Omnipod System communicates wirelessly, provides for automated cannula insertion and eliminates the need for multiple daily injection therapy or the use of pump and tubing.

IPG Photonics is a developer and manufacturer of a line of fiber lasers, fiber amplifiers and diode lasers that are used in various applications, primarily in materials processing. The company designs and manufactures a range of optical fiber-based lasers and amplifiers. The company also makes packaged diodes, direct diode lasers, laser systems and communications components and systems. A majority of the company's products are designed to be used as general-purpose energy or light sources.

iRhythm Technologies is a digital healthcare company redefining the way cardiac arrhythmias are clinically diagnosed by combining its wearable biosensing technology with cloud-based data analytics and capabilities. The company has developed a long-term continuous ambulatory cardiac monitoring platform known as the Zio service that provides continuous ambulatory cardiac monitoring through Zio XT monitor and Zio AT monitor. While wearing either the Zio XT or Zio AT monitor, patients can mark when symptoms occur by pressing a trigger button on the device and separately recording contextual data like activities and circumstances in a written symptom diary or digitally via the myZio application.

iRobot is a consumer robot company. The company's portfolio of solutions features technologies for the connected home and concepts in cleaning, mapping and navigation, human-robot interaction, and physical solutions. The company provides multiple Roomba floor vacuuming robots. The Braava robots automatically dust and damp mop hard-surface floors using cleaning cloths or the company's designed reusable microfiber cloths and include a reservoir that dispenses liquid throughout the cleaning cycle to keep the cloth damp. The robotic lawn mower, Terra t7 is being designed with a mapping and navigation system. Using the engaging Root Coding App, kids can learn coding fundamentals while they play, explore, and create.

Krystal Biotech is a gene therapy company which is engaged in the developing and commercializing treatments for patients suffering from dermatological diseases. The company has developed a gene therapy platform, which it refers to as the Skin TARgeted Delivery platform, that consists of engineered, patented, viral vector based on herpes simplex virus 1, and skin-optimized gene transfer technology, to develop off-the-shelf treatments for dermatological diseases. The company's primary candidate, KB103, a gene therapy product, is in preclinical development to treat dystrophic epidermolysis bullosa, a rare and severe genetic disease.

Lattice Semiconductor develops semiconductor technologies. The company delivers two types of semiconductor devices to its customers: Field Programmable Gate Arrays (FPGAs), and Video Connectivity Application Specific Standard Products (ASSPs). The company's FPGAs offerings consist of five product family lines: the ECP families, the MachXO families, iCE40 families, CrossLink, and Programmable Mixed Signal devices. The company's Video Connectivity ASSPs perform various functions, including ensuring interoperability, improving picture quality, converting between resolutions, and transmitting / receiving content without the need for additional components.

Logitech International is a holding company. Co. designs, manufactures and markets products that enable people to connect through music, gaming, video, computing, and other digital platforms. Co.'s products include: mobile speakers, which comprises portable wireless Bluetooth speakers; Audio-PC & Wearables, which comprises PC speakers, headsets, in-ear headphones and wireless audio wearable; gaming, which provides a range of gaming gear for gamers; video collaboration; home, which includes its home entertainment controllers and products dedicated to controlling emerging categories pointing devices; keyboards & combos; tablet & other accessories; and PC webcams.

Madrigal Pharmaceuticals is a clinical-stage biopharmaceutical company focused on the development and commercialization of therapeutic candidates for the treatment of cardiovascular, metabolic and liver diseases. The company's main product candidate, MGL-3196 (resmetirom), is a proprietary, orally administered, small molecule, liver-directed, thyroid hormone receptor-? selective agonist being developed as a once-daily oral pill that can potentially be used to treat a number of disease states including non-alcoholic steatohepatitis.

Minerva Neurosciences is a clinical-stage biopharmaceutical company focused on the development and commercialization of a portfolio of products candidates to treat patients suffering from central nervous system diseases. The company's product portfolio and potential indications include: roluperidone (also known as MIN-101) for the treatment of negative symptoms in patients with schizophrenia; seltorexant (also known as MIN-202 or JNJ-42847922), which the company is co-developing with Janssen Pharmaceutica NV, for the treatment of insomnia disorder and adjunctive treatment of Major Depressive Disorder (aMDD); MIN-117 for the treatment of MDD; and MIN-301 for the treatment of Parkinson's disease.

Moderna is creating a new generation of medicines based on messenger RNA to improve the lives of patients. The company uses its platform to identify and develop new mRNA medicines. When the company identifies a combination of platform technologies or programs across mRNA technologies, delivery technologies, and manufacturing processes that can enable shared product features across multiple potential mRNA medicines, it groups those programs as a modality. The company has created six modalities including prohylactic vaccines; cancer vaccines; intratumoral immuno-oncology; localized regenerative therapeuctics; systemic secreted therapeutics; and systemic intracellular therapeutics.

MongoDB operates as a general purpose database platform. The company's primary offerings are: MongoDB Enterprise Advanced, which includes the company's proprietary commercial database server, enterprise management capabilities, its graphical user interface, analytics integrations, technical support and a commercial license to its platform; MongoDB Atlas, which provides customers with automated provisioning and healing, system monitoring, managed backup and restore, default security and other features; and Community Server, which is a free-to-download version of the company's database that does not include all of the features of its commercial platform. The company also provides consulting and training to its customers.

Monolithic Power Systems is a fabless semiconductor company. The company designs, develops and markets power solutions for systems found in consumer, computing and storage, automotive, industrial, communications and consumer applications. The company's primary product families include the following: Direct Current (DC) to DC products, which are used to convert and control voltages within a range of electronic systems such as portable electronic devices, wireless Local Area Network access points, computers, and monitors, automobiles and medical equipment; and Lighting Control Products, which include lighting control integrated circuits that are used in backlighting and general illumination products.

NeuBase Therapeutics is a biotechnology company focused on developing therapies to treat rare genetic diseases and cancers caused by mutant genes. The company is developing antisense oligonucleotide therapies using its modular PATrOL? platform. The company's PATrOL?-enabled therapies act by binding to the mutant pre-RNA or messenger RNA primary sequence (or secondary or tertiary conformations) to prevent translation by ribosomes into mutant proteins or otherwise eliminate a pathogenic feature of the mutant transcript. The company's product pipeline comprised of NT0100 Program and NT0200 Program.

Neurocrine Biosciences is a commercial-stage biopharmaceutical company focused on discovering and developing treatments for patients with neurological, endocrine and psychiatric disorders. The company is primarily focused on the commercialization of INGREZZA? (valbenazine) in the United States. The company's late-stage pipeline includes opicapone as an adjunctive therapy to levodopa/DOPA decarboxylase inhibitors in adult Parkinson's disease patients, elagolix for the treatment of heavy menstrual bleeding associated with uterine fibroids in women, valbenazine for the treatment of chorea in adult patients with Huntington's disease and NBIb-1817 (VY-AADC) for the treatment of Parkinson's disease patients.

Nordson engineers, manufactures and markets differentiated products and systems used for dispensing, applying and controlling of adhesives, coatings, polymers, sealants, biomaterials, and other fluids, to test and inspect for quality, and to treat and cure surfaces. The company serves a range of consumer non-durable, consumer durable and technology end markets including packaging, nonwovens, electronics, medical, appliances, energy, transportation, building and construction, and general product assembly and finishing. The company has three operating segments: Adhesive Dispensing Systems, Advanced Technology Systems, and Industrial Coating Systems.

NVIDIA engages in graphics processing unit (GPU)-based visual computing and accelerated computing platforms. The company has two segments, GPU and Tegra Processor, which are based on a single underlying architecture. The company's GPU product brands are aimed at markets including GeForce for gamers; Quadro for designers; Tesla and DGX for artificial intelligence data scientists and big data researchers; and GRID for cloud-based visual computing users. The company's Tegra brand integrates an entire computer onto a single chip, and incorporates GPUs and multi-core CPUs to drive supercomputing for autonomous robots, drones, and cars, as well as for game consoles and mobile gaming and entertainment devices.

Proto Labs is a digital manufacturer of custom prototypes and production parts. The company's primary manufacturing product lines include Injection Molding, which uses three-dimensional (3D) computer-aided design-to-computer numerical control (CNC) machining technology for the automated design and manufacture of molds; CNC Machining, which uses commercially available CNC machines to provide milling and turning; 3D Printing, which includes stereolithography, selective laser sintering, direct metal laser sintering, Multi Jet Fusion and PolyJet processes; and Sheet Metal, which includes e-commerce-enabled custom sheet metal parts, providing customers with prototype and low-volume production parts.

Quidel is engaged in the development, manufacturing and marketing of diagnostic testing solutions. The company provides diagnostic testing solutions under various brand names, including, among others, the following: Quidel?, QuickVue?, QuickVue+?, Sofia?, Triage?, AmpliVue?, Solana?, Virena?, MicroVue?, Lyra?, FreshCells?, D3?, FastPoint?, ReadyCells?, Super E-Mix?, InflammaDry?, AdenoPlus?, ELVIRA?, ELVIS? and Thyretain?. The company's diagnostic testing solutions are separated into its four product categories: rapid immunoassay, cardiac immunoassay, specialized diagnostic solutions and molecular diagnostic solutions.

Range Resources is a holding company. Through its subsidiaries, the company is an independent natural gas, natural gas liquids and oil company, engaged in the exploration, development and acquisition of natural gas and oil properties, located in the Appalachian and North Louisiana regions of the United States, primarily in the Marcellus Shale in Pennsylvania and the Lower Cotton Valley formation in Louisiana.

RingCentral is a provider of software-as-a-service solutions. The company's product portfolio, among others, includes: RingCentral Office, which provides a unified activity for communication and collaboration across multiple modes; RingCentral Meetings, which is a collaborative meetings solution that provides web meetings, video conferencing, and screen sharing integrated with team messaging; RingCentral Professional, which is a cloud based virtual telephone service offering designed for personnel who are on the go; and RingCentral Fax, which provides online fax capabilities that allow businesses to send and receive fax documents without the need for a fax machine.

Roper Technologies designs and develops software and engineered products and solutions for a variety of end markets. The company has four segments: Application Software, which includes Aderant, CBORD, CliniSys, and Data Innovations; Network Software and Systems, which includes ConstructConnect, DAT, Foundry, Inovonics; Measurement and Analytical Solutions, which includes Alpha, CIVCO Medical Solutions, CIVCO Radiotherapy, Dynisco, FMI, Hansen, Hardy, IPA, Logitech, Neptune, Northern Digital, Struers, Technolog, Uson, Verathon; and Process Technologies, which includes AMOT, CCC, Cornell, FTI, Metrix, PAC, Roper Pump, Viatran, Zetec.

Sarepta Therapeutics is a commercial-stage biopharmaceutical company focused on the discovery and development of RNA-targeted therapeutics, gene therapy and other genetic therapeutic modalities for the treatment of diseases. The company is developing therapeutic candidates for a range of diseases and disorders, including Duchenne muscular dystrophy (DMD), Limb-girdle muscular dystrophies, Mucopolysaccharidosis type IIIA and other neuromuscular and central nervous system. The company's commercial product, EXONDYS 51? (eteplirsen) Injection is indicated for the treatment of DMD in patients who have a confirmed mutation of the DMD gene that is amenable to exon 51 skipping.

Scotts Miracle-Gro is a manufacturer and marketer of consumer lawn and garden products in North America. The company's segments are: United States Consumer, which consists of the company's consumer lawn and garden business located in United States; Hawthorne, which consists of the company's indoor, urban and hydroponic gardening business; and Other, which consists of the company's consumer lawn and garden business in geographies other than the United States and the company's product sales to nurseries, greenhouses and other customers. The company manufactures, markets and sells lawn and garden products in the following categories: lawn care, gardening and landscape, hydroponics, and controls.

ServiceNow provides enterprise cloud computing services that define, structure, manage and automate digital workflows for global enterprises. The company markets its services to enterprises in a variety of industries, including consumer products, education, financial services, government, health care, information technology (IT) services and technology. The company sells its subscription services through direct sales and, to a lesser extent, through indirect channel sales. The company also provides a portfolio of personnel and other services, both directly and through its network of partners. The company's products include IT service management, IT operations management, IT business management, and security operations.

Skyworks Solutions is a provider of analog semiconductors that connect people, places, and things, spanning a number of applications within the aerospace, automotive, broadband, cellular infrastructure, connected home, industrial, medical, military, smartphone, tablet and wearable markets. The company's product portfolio consists of various solutions, including: amplifiers, antenna tuners, attenuators, circulators/isolators, wireless analog system on chip, direct current (DC)/DC converters, demodulators, detectors, diodes, directional couplers, diversity receive modules, filters, front-end modules, hybrid, light emitting diode drivers, low noise amplifiers, mixers, and modulators.

Spartan Motors is engaged in vehicle manufacturing and assembly for the commercial vehicle, emergency response and recreational vehicle industries. The company's segments are: Fleet Vehicles and Services, which manufactures commercial vehicles used in the e-commerce/last mile/parcel delivery and mobile retail industries; Emergency Response Vehicles, which engineers and manufactures custom emergency response cabs and chassis and apparatus; and Specialty Chassis and Vehicles, which engineers and manufactures Class A diesel motor home chassis, manufactures its Reach walk-in van, provides contract assembly of defense vehicles and other chassis, and distributes related aftermarket parts and accessories.

Splunk provides software solutions that enable users to investigate, monitor, analyze and act on machine data. The company's main product is Splunk Enterprise, a machine data platform, comprised of collection, indexing, search, reporting, analysis, alerting, monitoring and data management capabilities. The company's Splunk Cloud delivers the capabilities of Splunk Enterprise as a service, while Splunk Light provides log search and analysis for information technology environments. The company also provides services that include maintenance and customer support, training services to its customers and channel partners, as well as consulting and implementation services to customers through its services team.

Stamps.com is a provider of Internet-based mailing and shipping solutions. The company's software solutions allow customers to print mailing and shipping labels for multiple carriers through downloadable software, web-based user interfaces and application programming interfaces. The company's solutions provide its customers with access to discounted carrier including the United States Postal Service and United Parcel Service. The company's customers primarily include small businesses, home offices, medium-size businesses, enterprises, e-commerce merchants, retailers and shippers including warehouses, fulfillment houses and omni-channel retailers. The company's operations consist of two segments Stamps.com and MetaPack.

Tenable Holdings is a provider of solutions for a category of cybersecurity called Cyber Exposure. Cyber Exposure manages, measures and compares cybersecurity risk. The company's platform offerings provide visibility into security issues such as vulnerabilities, misconfigurations, internal and regulatory compliance violations and other indicators of the state of an organization's security. The company's enterprise platform offerings include Tenable.io, which is the company's software as a service offering, and Tenable.sc, which is the company's on-premises offering, both of which provide organizations with applications purpose-built for areas of attack surfaces.

Thor Industries is a manufacturer of recreational vehicles. The company has three segments: North American Towable Recreational Vehicles, which consists of: Airstream (towable), Heartland (including Bison, Cruiser RV and DRV), Jayco (including Jayco towable, Starcraft and Highland Ridge), Keystone (including CrossRoads and Dutchmen) and KZ (including Venture RV); North American Motorized Recreational Vehicle, which consists of: Airstream (motorized), Jayco (including Jayco motorized and Entegra Coach) and Thor Motor Coach; and European Recreational Vehicles, which consists of the Erwin Hymer Group business.

Translate Bio is a clinical-stage messenger RNA (mRNA) therapeutics company. The company is engaged in developing medicines to treat diseases caused by protein or gene dysfunction. Using its proprietary mRNA therapeutic platform (MRT platform), the company creates mRNA that encodes functional proteins. The company is developing its MRT product candidate for the lung, MRT5005, for the treatment of cystic fibrosi, and MRT5201, for the treatment of ornithine transcarbamylase deficiency.

Trex Company is a manufacturer of composite decking and railing products, which are marketed under the brand name Trex?. In addition, the company is a national provider of custom-engineered railing and staging, systems for the commercial and multi-family market, including sports stadiums and performing arts venues. The company operates in two reportable segments: Trex Residential Products, which provides a set of product offerings in the decking, railing, fencing, steel deck framing, and outdoor lighting categories; and Trex Commercial Products, which designs and engineers custom railing solutions, which are used in collegiate sports facilities, standardized architectural and aluminum railing systems.

Twist Bioscience is a synthetic biology company. The company is developing a disruptive DNA synthesis platform to industrialize the engineering of biology. The main of its platform is a proprietary technology that manufactures synthetic DNA by writing DNA on a silicon chip. The company has combined this technology with proprietary software, scalable commercial infrastructure and an e-commerce platform to create a technology platform. The company's offerings consists of two primary products that address different needs of its customers across a variety of applications: synthetic genes, oligonucleotide (oligo) pools, next generation sequencing tools and DNA libraries.

Ubiquiti is engaged in providing portfolio of networking products and solutions for operator-owners of wireless internet services (WISP's), enterprises and smart homes. The company's operator-owner service provider product platforms provide carrier-class network infrastructure for fixed wireless broadband, wireless backhaul systems and routing and the related software for WISP's to control, track and bill their customers. The company's enterprise product platforms provide wireless LAN (WLAN) infrastructure, video surveillance products, switching and routing solutions, security gateways, and other complimentary WLAN products along with a software platform.

United States Steel is a steel producer of flat-rolled and tubular products with production operations in the United States and Europe. The company is also engaged in railroad services and real estate operations. The company's segments are: North American Flat-Rolled, which produces slabs, strip mill plates, sheets and tin mill products; U. S. Steel Europe, which produces and sells slabs, strip mill plate, sheet, tin mill products and spiral welded pipe, as well as heating radiators and refractory ceramic materials; and Tubular Products, which produces and sells electric resistance welded steel casing and tubing (known as oil country tubular goods), and standard and line pipe and mechanical tubing.

United Therapeutics is a biotechnology company. The company markets and sells four commercial therapies to treat pulmonary arterial hypertension (PAH): Remodulin? (treprostinil) Injection; Tyvaso? (treprostinil) Inhalation Solution; Orenitram? (treprostinil) Extended-Release Tablets; and Adcirca? (tadalafil) Tablets. The company also markets and sells an oncology product, Unituxin? (dinutuximab) Injection for treatment of high-risk neuroblastoma. The company also engages in research and development of new indications and formulations and delivery devices for its existing products, as well as new products to treat PAH and other conditions. The company also engages in organ transplantation-related technologies.

Vertex Pharmaceuticals is focused on developing and commercializing therapies for the treatment of cystic fibrosis (CF) and developing research and development programs in other indications. The company's marketed products are TRIKAFTA (elexacaftor/tezacaftor/ivacaftor and ivacaftor), SYMDEKO/SYMKEVI (tezacaftor in combination with ivacaftor), ORKAMBI (lumacaftor in combination with ivacaftor) and KALYDECO (ivacaftor), which are approved to treat patients with CF who have specific mutations in their cystic fibrosis transmembrane conductance regulator gene. The company is evaluating CTX001, a genetic therapy as a potential treatment for sickle cell disease and beta-thalassemia.

West Pharmaceutical Services is a manufacturer in the design and production of containment and delivery systems for injectable drugs and healthcare products. The company's products include packaging, containment solutions, reconstitution and transfer systems, and drug delivery systems, as well as contract manufacturing, analytical lab services and integrated solutions. The company's segments are: Proprietary Products, which provides packaging, containment and drug delivery products, analytical lab services and integrated solutions; and Contract-Manufactured Products, which is focused on the design, manufacture, and automated assembly of devices, for pharmaceutical, diagnostic, and medical device customers.

Winnebago Industries is a manufacturer with a portfolio of recreation vehicles and marine products used primarily in leisure travel and outdoor recreation activities. The company's reportable segments include: Towable, which is comprised of products which are not motorized and are generally towed by another vehicle as well as other related manufactured products and services; and Motorhome, which is comprised of products that include a motorized chassis as well as other related manufactured products and services. The company's subsidiary, Chris-Craft USA, Inc., manufactures and sells boats in the recreational powerboat industry through a network of independent authorized dealers.

Wix.com develops and markets an internet service that allows users to create web content. Co. is a global web development platform enabling businesses and organizations to take their businesses, brands and workflow online. Co.'s core product is the Wix Editor, a drag-and-drop visual development and website editing environment complete with high quality templates, graphics, image galleries and fonts. With Co.'s platform, Wix registered users can create and manage a professional quality digital presence tailored to their business and brands' specific look and feel that is accessible across all major browsers and the most widely used desktop, tablet and mobile devices.

Y-mAbs Therapeutics is a biopharmaceutical company focused on the development and commercialization of antibody-based therapeutic products for the treatment of cancer. The company has a range of product pipeline, including two pivotal-stage product candidates: naxitamab and omburtamab, which target tumors that express GD2 and B7-H3, respectively. The company is developing naxitamab for the treatment of pediatric patients with relapsed or refractory, high-risk neuroblastoma (NB), and radiolabeled omburtamab for the treatment of pediatric patients with central nervous system, leptomeningeal metastases, from NB.